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Increasing the intravascular volume prior to diuresis could temporarily reduce neurohormonal sodium retention (e.g

There was no lymphadenopathy, clubbing, or pedal edema

While most of the current studies have been conducted in animal models, the results are impressive

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SGLT-2 inhibitors and thiazolidinediones may also be used concurrently, though patients should be monitored for any unexpected interactions or adverse effects