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Great strides have been made when it comes to GLP-1 outcomes, and people are increasingly turning to these medications for weight loss or chronic conditions through insurance or self-pay with FDA-approved or compounded medications
It is also possible that some of the effects of GLP-1 agonists on food intake may be mediated by interaction with sensory afferent neurones of the vagus nerves in the gastrointestinal tract
Katsiampoura A, Raghav K, Jiang ZQ, Menter DG, Varkaris A, Morelli MP, Manuel S, Wu J, Sorokin AV, Rizi BS, Bristow C, Tian F, Airhart S, Cheng M, Broom BM, Morris J, Overman MJ, Powis G, Kopetz S
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This pattern fits with the fact that central GLP-1 can inhibit feeding behaviours independently from GLP-1-gut-brain signalling 7