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GLP-1 agonists are injectable or oral medications that mimic glucagon-like peptide-1, a natural hormone regulating appetite, satiety, and blood glucose

Mol Pharmacol 65 : 10701079

These effects of Pycnogenol supplementation on blood pressure were investigated in a small RDP crossover study with eleven borderline hypertension patients ( supplementation with 200 mg a day for eight weeks significantly lowered blood systolic blood pressure from 140 to 133 mmHg compared to placebo, which was decreased only marginally