1999 Sep 1;40(3):21125
While it can help preserve muscle during weight loss, it is not designed to directly promote muscle gain
While randomized controlled trials (RCTs) established the efficacy and general safety of these agents, RCT protocols often underrepresent real-world patient complexity, heterogeneous comorbidities, and long-term adherence barriers
The majority of instances were during dosage escalation
Nevertheless, based on the promising pre-clinical and early-phase clinical trial findings in the colorectal cancer setting [12, 13, 32, 151], a Chinese phase III trial aiming to evaluate the effectiveness of combing high dose IV VitC (1.5 g/kg) with FOLOX +/ bevacizumab versus treatment with FOLFOX +/ bevacizumab alone as first-line therapy in patients with recurrent or advanced colorectal cancer is currently ongoing (ClinicalTrials.gov Identifier: NCT02969681, Table 3, recruiting status unclear)
The consultation helps the prescriber check eligibility, medical history, current medicines and possible safety concerns
