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10.1186/s12864-017-3642-5 142 SellamA.DongoA.GuillemetteT.HudhommeP.SimoneauP

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A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)

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19shows almost complete protection of outer hair cells from cisplatin-induced degeneration in a cochlear explant model with 1.5 hour pretreatment followed by co-treatment with the otoprotectant 6-thioguanine with 10 M cisplatin.FIG