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The association of ROS with neuronal degeneration in PD is further substantiated by modeling the Parkinsonian phenotypes in animals through 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), rotenone, 1,1-dimethyl-4,4-bipyridinium dichloride (paraquat), or 6-hydroxydopamine (6-OHDA), those are known of elevate the oxygen free-radicals in the cell 18

3 , 4 The association between endometriosis and reduced fertility is well documented

Holdiness MR

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However, the clinical meaning of this observation is unclear.20 Anti-allergic effect of biologically active polysaccharides animal experiments There are several experimental animal models of allergic and oncologic diseases which, besides the series of in vitro studies, showed that -glucans possess an anti-allergic and immunomodulation effect

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