Castronovo C, Rossetti R, Rusconi D, Recalcati MP, Cacciatore C, Beccaria E, et al
The extracellular matrix: not just pretty fibrils
The "rapid reversal" group (approximately 10-15% of users) experiences concerning quick benefit loss within weeks of discontinuation, typically involving users who applied very high concentrations creating dependency-like patterns, possessed severe underlying skin conditions requiring ongoing treatment, experienced significant lifestyle or environmental stressors overwhelming skin resilience, discontinued abruptly without tapering from high-dose protocols, or had unrealistic perception inflation during treatment leading to exaggerated reversal perception
Some peptides have immune effects as well
Liposomal formulations are designed to improve stability and bioavailability, she adds
14 days at 28 C protected from light