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Although the clinical trial results for Gln metabolism inhibitors have not been satisfactory thus far, a substantial body of prior research has provided a scientific foundation for investigating the targeting of tumor Gln metabolism

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Further research discovered that a diet rich in vitamins and minerals, particularly lutein and zeaxanthin may delay the development of cataracts (9, 10, 11, 12, 13, 14)

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Although the exact mechanism by which glucose reprograming contributes to tumorigenesis remains unclear, numerous genetic and pharmacological studies showed that this metabolic switch can be essential for cancer survival and proliferation