Their actions alter the excitatory/inhibitory balance, which is beneficial for plasticity in normal physiology but pathological when dysregulated
Al-Oqail MM, Al-Sheddi ES, Farshori NN, Al-Massarani SM, Al-Turki EA, Ahmad J, Al-Khedhairy AA, Siddiqui MA
doi: 10.1038/s41541-021-00294-8 300 OliverJ
Zhao, Y., Vanhoutte, P
A scientific review of four small-scale studies confirmed that glutathione use does result in some skin lightening.24 Additionally, glutathione has also been shown to decrease psoriasis when levels are bolstered by intake of whey protein, which contains glutamylcysteine, a precursor to GSH.25 Most impressively, perhaps the same studies mentioned above also show that glutathione doesn't just lighten, but it improves skin elasticity and decreases wrinkles' appearance
At present, it remains unclear whether there are numerous key mechanisms involved across various disorders or whether mechanisms are disorder specific
