glutathione peroxidase 3 is a potential biomarker for konzo The mitochondrial isoform glutathione peroxidase

The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans

Am J Physiol Lung Cell Mol Physiol 2007

The mice were fed standard laboratory chow and water

Conversely, lowering the dose may render the treatment ineffective

The current findings disagree with Wantanable and colleagues , who observed a good evidence favoring efficacy of topical oxidized glutathione 2% lotion when applied twice daily for 10 weeks in producing skin whitening and also statistically significant reduction of skin melanin index by using Mexameter (a tool objectively measures melanin index of the skin) compared with placebo

After its synthesis, GSH is delivered to some intracellular compartments, including mitochondria, endoplasmic reticulum, nucleus, and to the extracellular space (e.g., blood plasma and bile) for utilization by other cells and tissues (Forman et al., 2009)