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Additionally, most providers may prefer a once-weekly schedule with titration adjusted based on clinical judgment

An increased risk was also supported by results of a large meta-analysis comprising a total of 36 double-blind randomized clinical trials with DPP-4 inhibitors with a total of 54,664 patients: there was a 58% increased risk of acute pancreatitis with DPP-4 inhibitors compared with other therapies (127)

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When you start an obesity management medication, it's always in addition to lifestyle therapy, she said

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If you find that any side effects persist for longer than this or get worse over time, stop taking your medication and contact your prescriber as soon as possible