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Phentermine/topiramate is associated with the highest proportion of fatal cases (6% of its reported AEs)
Methods Study Design This was a phase 4, 34- to 44-week, multicentre, prospective, non-interventional, single-arm study conducted in real-world settings at 27 sites in the Netherlands
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Val3-Asp4 interact with similar residues at the base of the binding cavity to those observed for residues 2 and 3 of the other peptides, however, with the exception of Y148 1.43 , these were very transient (Supplementary Table 3)
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