With the GSH-ee experiments, mice were injected intraperitoneally with either vehicle (saline) or Glutathione ethyl ester (Cayman Chemical, 14953) for 4 days ((17-20) days post AAV-TBG-Cre treatment)
Avocado: Contains glutathione directly, as well as compounds that help increase its production
Doses vary widely in the literature, but ~1.5-3 grams IV q6hr seems reasonable
Brain & Nerve Protection: Potential neuroprotective effects support focus, memory, and long-term brain health
5-Amino-1MQ has shown a high safety profile in animal models because it acts very specifically on adipose tissue and does not cross the blood-brain barrier, avoiding central nervous system stimulation
Companies that recognise and respond to these shifts will be best placed to succeed, while those slow to adapt risk losing relevance in an increasingly complex and dynamic landscape