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doi: 10.3389/fphar.2025.1513125 Received 17 October 2024 Accepted 07 March 2025 Published 28 March 2025 Volume 16 - 2025 Edited by Eliot Ohlstein, Drexel University School of Medicine, United States Reviewed by Robertas Badaras, Vilnius University, Lithuania Qiyan Wang, University of Michigan, United States Updates Copyright 2025 Di Fulvio, Rathod and Khader