As Ca 2+ is required for many NK cell functions, including cytotoxic activity, formation of the immune synapse, the granule-dependent pathway of apoptosis, microtubule reorganisation and cytokine gene transcription [62, 196], impaired TRPM3-dependent Ca 2+ signalling may contribute to the NK cell dysfunction seen in ME/CFS
Research indicates that GHK-Cu can upregulate TGF- receptor expression on fibroblasts, effectively sensitizing these cells to pro-collagen signals
Common mild side effects include red urine, soreness at the injection site, or a mild rash
However, in patients with pernicious anaemia or malabsorption, these stores cannot be replenished through diet, making regular injections essential
By supporting glycosaminoglycan production, GHK-Cu can improve how well skin holds moisture
Independently tested by a USA-based third-party laboratory