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Adequate Vitamin B12 levels contribute to better overall health, reduced risk of anemia, improved nerve health, and enhanced energy levels

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Paricasitol as a VDR agonist can inhibit ferroptosis by activating VDR/Nrf2/HO1 signaling pathway in DN, which effectively attenuates iron deposition in renal tubular epithelial cells and renal damage after diabetic injury [82]

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Preclinical studies suggest it modulates nitric oxide pathways and growth-factor expression to promote angiogenesis and collagen deposition in damaged tissues [1] [3]

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