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Those with long-term vitamin B12 deficiency need hydroxocobalamin 1000 mcg shots daily for one week, followed by weekly injections for two months

It also significantly improves insulin resistance, optimizes the body's glucose utilization efficiency, and reduces the damage caused by lipotoxicity to bodily tissues

These improvements in echocardiographic parameters are indicative of a direct positive impact on RV performance [15]

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Maintaining adequate protein intake, engaging in resistance exercise, ensuring sufficient sleep, and achieving gradual rather than excessively rapid weight loss can help preserve hormonal balance and lean body mass during treatment