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As transdermal delivery of human growth hormone using MNs prepared by carboxymethylcellulose and trehalose demonstrated a short t max (~30 min) after MN application and exhibited similar pharmacokinetic profiles with that of the SC injection [19], the GSH-HA patch with fast water-absorption properties would be applicable for systemic GSH delivery

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PubMed Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P (2006)

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