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Insurers in some markets are facing mounting market pressure to remove the exclusion on weight management to promote inclusivity, resulting in the imminent exposure of insurers in these markets to reimbursement of this class of drugs

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At that point, management had visibility on pricing mechanics but limited real-world data on refill rates, persistence, dose escalation, and cross-channel acceleration

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A clinician can provide personalized dosing, lifestyle coaching, and ongoing support

Figure 3: Homocysteine (Hcy) follows two pathways in cells: one turns it into methionine, and the other into cystathionine