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Responses of gonadal transcriptome and physiological analysis following exposure to 17-ethynylestradiol in adult rare minnow Gobiocypris rarus

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Modern English references (Ashmarin 2010, Levitskaya 2004, Myasoedov 2017) provide bibliographic entry points to systematically deepen before designing a protocol, to avoid reinventing results already published 30 years ago in a less accessible language

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Each 17-day course should be followed by a pause of at least four months

Subcutaneous injections exceeding 0.5mL per site reduce absorption efficiency due to depot formation, which is why protocols exceeding 125mg daily should split doses across multiple injection sites or use oral administration instead