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60 These observations highlight the necessity of disease-stage-specific and quantitatively controlled autophagy modulation

10.1038/s41430-021-00996-1 50

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The k red value of 1.4 10 6 M 1 s 1 for PfGrx C88S (SH) 2 is about two orders of magnitude higher than the highest k ox value for PfGrx C32S/C88S (SSG) in accordance with a physiological relevance of glutaredoxins as deglutathionylating enzymes