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Side effects were qualitatively similar with semaglutide, as expected: nausea (52% of patients), diarrhea (27%) and vomiting (24%) being a few of the most common

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In particular, the glutamate-generating metabolism seems essential, as shown by a complete depletion of Gln during H

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DPP-4 is responsible for the inactivation of GLP-1 by cleaving two N-terminal amino acids proline or alanine from natural peptides in the penultimate (P1) position