nejm tirzepatide A 3-year study of in participants with obesity and prediabetes showed substantial and sustained weight reduction and decreased risk of progression to diabetes with tirzepatide, as compared with placebo. Full SURMOUNT-1 Tirzepatide vs Semaglutide: 2025 NEJM

Important Safety Information and Contraindications While Tirzepatide offers significant benefits, its not a one-size-fits-all solution

This is why men who start tirzepatide with very low testosterone often experience an initial dip in sexual function followed by significant improvement as the weight comes off

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Balancing blood sugar GLP-1 medications help regulate blood sugar

These minor side effects include: Reduced appetite Nausea Vomiting Diarrhea Headaches Dizziness These minor side effects are most common when patients begin taking their prescription GLP-1

These drugs are not metabolized by CYP3A4, so grapefruit does not affect them