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Collen, M

It is activated by voltage-dependent Ca 2+ -channels, as well as neurotransmitter and hormone receptors, that increase intracellular Ca 2+ and cause accumulation of the Ca 2+ -calmodulin complex

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In resting cells, GHK-Cu produces modest ERK1/2 activation supporting proliferative responses, while in inflammatory conditions, the peptide suppresses p38 and JNK activation, contributing to anti-inflammatory effects

J Hazard Mater Adv 10:100254 Xue L et al (2021) Efficiency and mechanism of reducing ammonia volatilization in alkaline farmland soil using Bacillus amyloliquefaciens biofertilizer