Barkats M, Millecamps S, Abrioux P, Geoffroy MC, Mallet J
Another essential component concerns pharmacokinetics (PK) and pharmacodynamics (PD)
Archived from the original on April 23, 2023
Since these unstable compounds strongly attract other molecules with an electron to pair up, they can damage proteins, DNA, and lipids
Topical application of GHK-Cu accelerates wound closure (full-thickness excisional wounds in rodents, wound area tracing, digital planimetry), increases granulation tissue thickness (H&E histology), promotes re-epithelialisation (K14/K5 basal keratinocyte IHC, Ki-67 proliferation), and reduces scar width and fibrosis (Massons trichrome, collagen bundle organisation by SHG microscopy)
35 It is also shown that iron deficiency promotes glycolysis by limiting oxidative metabolism, affecting carbohydrate and fat catabolic processes, and leading to skeletal muscle energy disorders