Emphasizing a nutrient-dense diet rich in protein, essential amino acids, and micronutrients, along with supplements such as creatine, omega-3 fatty acids, and magnesium, can help support tissue repair and reduce inflammation
It is a core component of an already FDA-approved commercial drug
Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025
Injectable Injectables are still the most widely used GLP-1 format and for most people, they remain the most cost-effective option, especially through compounded programs
PLoS ONE 12:e0184764
Microglia constitute the first line of immune defense