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Furthermore, it conjugates with toxins in the liver via Glutathione S-transferase (GST) , facilitating their excretion [4]

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The possible mechanisms of their protective effects may be associated with the decrease of p16-, p21 expressing cells and the downregulation of senescence-associated secretory phenotype (including the expression of pro-inflammatory cytokines IL-6, IL-1, and MMP-9) ( 4.5 Other renal disorders Dietary intake of the flavonoid quercetin has been proven effective in lowering blood pressure and restoring endothelial dysfunction in animal models of hypertension

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