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IGF-1 is a growth factor that promotes cell proliferation

Sci Rep 2017;7:9452.ArticlePubMedPMC 66

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In mammals, acute inflammation induced by intramyocardial injection of immunogenic zymosan A particles stimulates cardiomyocyte proliferation in neonatal mice, while cardiac injury-induced regenerative response was suspended after immunosuppression 41

The amount discarded should be documented in the medical record and the J-code billed to reflect total units in the vial, with modifier JW distinguishing the administered portion from the discarded portion