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When applied to tenocyte culturescells that make up the tendonsIGF-1 stimulates these cells to proliferate and produce more extracellular matrix components, including collagen

In practical terms that means deeper sleep, better recovery, improved body composition, and over months, meaningful shifts in lean muscle, fat distribution, skin quality, and overall steady-state energy

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Topical and injectable GHK-Cu preparations have documented effects on collagen synthesis, skin firmness, fine lines, and wound healing in published studies

10.1016/j.exer.2021.108723 107 Lpez-LluchG

The produced H 2 O 2 enters the cells via aquaporin, the protein channel generally associated with water transport, and triggers the activation of the NRF2 factor [160]