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While moderate ROS levels are necessary for physiological signaling and tissue remodeling, excessive oxidative stress can disrupt redox homeostasis, leading to persistent inflammation and fibrosis in the lung [58,59,60]

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Furthermore, inhibiting antiporter uptake of cystine interferes with the presentation of exogenous antigen to MHCII-restricted T cells and blocks cross-presentation on MHCI (71)

2 Recently, microbiota-directed food invention, which was developed to exert therapeutic effects through the manipulation of gut microbiota components, was found to be an effective dietary supplementation strategy for undernourished children

doi: 10.4132/jptm.2017.01.04 12 AprileIScottCACervesatoDBeltramiCAMeoAFabrisG