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Another study conducted in 158 healthy male volunteers assessed the impact of different water volumes and post-dosing fasting periods on semaglutide exposure, and the authors concluded that administration of oral semaglutide in the fasting state with up to 120 mL of water and a post-dose fasting period of at least 30 min resulted in clinically relevant semaglutide exposure [31]
A strong therapeutic alliance between patient and provider is fundamental to achieving optimal outcomes while maintaining safety in this population with coexisting conditions
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The evidence therefore supports an individualised approach rather than a universal recommendation
10.1111/nmo.13884 Neurogastroenterol Motil
A plateau at this stage is likely a sign of reaching maximum medication effect rather than a problem to fix
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