References NHS England: Implementation of NICE TA1026 for Tirzepatide (Mounjaro) NHS England: Medicines for obesity Focus On: Tirzepatide for Weight Management in General Practice (2025) Senedd Research: What next for weight-loss medication in Wales
Tapering versus abrupt cessation The clinical trials did not specifically study tapering protocols, but physiological principles suggest a gradual dose reduction may produce a smoother transition than abrupt cessation
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