Albini A, Sporn MB
Practical Application Consistent sleep schedule: Same bedtime/wake time, including weekends 7-9 hours nightly: Inadequate sleep duration increases DPP-4 Sleep quality: Deep, uninterrupted sleep matters more than just duration Light exposure: Bright light morning, dim light evening supports circadian rhythm Eat larger meals earlier in the day when DPP-4 activity is naturally lower Avoid late-night eating when DPP-4 activity peaks Morning protein intake may benefit from lower DPP-4 activity Strategy 6: Managing Inflammation and Metabolic Stress The Science: Chronic low-grade inflammation and metabolic stress significantly upregulate DPP-4 expression
Advances in Microbiology, 5 , 479492
The decision by CMS also opens the door for coverage for additional indications including chronic kidney disease, obstructive sleep apnea and Alzheimers
Brown LS, Foster CG, Courtney JM, King NE, Howells DW, Sutherland BA
Research in animal models of Alzheimers disease suggests these drugs may have neuroprotective effects, reduce early forms of amyloid, normalize the brains processing of glucose, and improve memory and learning
