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Among these, artesunate, sevoflurane, dihydroartemisinin, brusatol, nisin, hederagenin, glaucocalyxin A, nootkatone, cannabinoids and ophiopogonin B successfully promote ferroptosis in diverse cancer cell types mediated by the ER stress branch ATF4-CHOP-CHAC1 (Lu et al., 2024
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The primary mechanisms of organs and tissues damage include inflammation, oxidative stress, cell apoptosis or pyroptosis, metabolic disturbances, and fibrosis
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