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Negative regulation of stress-activated MAPK signaling in Arabidopsis

181 TardatM.DjardinJ

Nature Scientific Reports 2016 comparative study showed GHK-Cu produced no cytotoxicity to human keratinocytes at concentrations up to 5,800 M over 72 hours and did not induce inflammatory biomarkers unlike other copper compounds

Primarily, they found that increased carnosine levels may play an important role in antioxidant production, which can scavenge harmful substances such as reactive oxygen species (ROS) which are linked to cell damage and diseases such as cancer [25]

References Lessard C et al

Overall, the drug was well-received with no other significant adverse events reported (NCT01265498)