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FIGURE 3 TABLE 2 Outcomes of pancreatitis associated with the use of GLP-1 RA

Given the severe lipodystrophy in our mouse model, our data also reveal that GLP-1 receptor activation can improve insulin sensitivity and metabolic health independent of adipose tissue, providing additional novel mechanistic insight

While short-term side effects like nausea and gastrointestinal issues are common, long-term effects require careful monitoring and management

It is important to note that women of childbearing age should be on contraception while on ACEi or ARBs and guidelines recommend stopping these agents if pregnancy were to occur due to their teratogenic effects (17, 18)

Microsurgery 42 (5), 433440

VE is an antioxidant substance that exists in the intestinal cell basement, and lipid peroxidation is produced by the interaction between free radicals and polyunsaturated fatty acids