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Instead of waiting for treatment failure, structured response evaluations permit: Timely intervention for early non-responders Preservation of patient motivation and engagement More efficient resource allocation Insurance and access considerations for AOMs Access limitations pose substantial barriers for GLP-1 non-responders seeking alternative treatments

These establish a reference point for monitoring treatment effects and safety

Ertugliflozin and sitagliptin co-initiation in patients with type 2 diabetes: the VERTIS SITA randomized study

Substantial weight loss achieved through GLP-1 therapy might therefore improve RA symptoms by reducing this inflammatory burden

USCs study reported $175 billion in cost offsets (not savings, as the USC study did not estimate what it would cost Medicare to cover GLP-1s) for Medicare over 10 years through GLP-1 coverage