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Vascular smooth muscle cell peroxisome proliferator-activated receptor protects against endothelin-1-induced oxidative stress and inflammation

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Cao Y, Qu HJ, Li P, Wang CB, Wang LX, Han ZW

It is a peptide initially established as a murky tanning product

Based on limited human pharmacology data, ipamorelin appears relatively selective, with less pronounced effects on cortisol and prolactin secretion compared with some other GH secretagogues though this selectivity has not been extensively validated in large human trials

It also explains why weight loss outcomes vary