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Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial

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Indeed, the novel melanocortin candidate AP1189, currently in phase II trials, may have been discarded early during development as it does not induce cAMP, but activates ERK1/2 phosphorylation instead (176), indicating that at least when addressing the anti-fibroblast activities of MC compounds, other pathways should be considered

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Therefore, higher plasma TMAO in humans was suggested as a marker of kidney damage [79]