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According to the FDA labeling, there is no clinically meaningful difference in absorption between these sites

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The consultation focuses on education, safety, and helping you understand what will happen once treatment begins

In November 2023, the FDA granted approval for Zepbound (tirzepatide) for chronic weight management in adults with obesity (body mass index 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition such as hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease