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Remarkably, low dietary fiber intake reduces beneficial bacteria capable of fermenting dietary fiber to produce SCFAs

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Additional studies describe exploratory evaluation of intracellular signaling dynamics, NAD-related metabolic networks, and methylation-associated processes examined in non-clinical research settings

Increased autophagy was apparent, as reflected by increased LC3 expression, autophagic vacuoles, and autophagic flux

MAPK/ERK activation runs in parallel, influencing cell cycle progression and proliferation