Suppression of steroid 5-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma
The endocrine hypothesis of ageing proposes that hormones govern ageing, with the evolutionary conserved insulin/IGF-1 signalling pathway playing a key role in hormonal ageing regulation (Tullet et al., 2014)
The mitochondrial UPR: mechanisms, physiological functions and implications in ageing
Key scientific figures and citations Cagrilintide is a long-acting amylin analogue that, when combined with semaglutide, produced clinically meaningful and dose-dependent weight loss in adults with overweight or obesity. Enebo LB
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Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis