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Mice with ghr Box1 deletion by substitution of each proline in the Box1 to alanine (which eliminates JAK2 binding and signaling, while still allowing signaling to occur via the SFKERK1/2 pathway) have obstructed growth with a similar phenotype observed in mice with ghr KO (109, 110)

It has been proven that it expresses antioxidant capabilities in vitro

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The branches of the superior hypophyseal artery form the hypophyseal portal system (see Figure 3

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