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In a casecontrol analysis, there was a mildly increased risk of prolactinoma with menopausal hormone therapy as well as with combined oestrogenprogesterone oral contraceptives, but the risk with oral contraceptives was not present in the prospective cohort analysis 43 (see Supplementary Box 3 for discussion of prolactin excess in pregnancy)

It also indicates that the uterine fluid is a low-glucose environment, which is consistent with the research of Harris et al., which also reported that glucose in the uterine fluid is 725 times lower than that in the blood (Harris et al., 2005)

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Despite this, there is no conclusive evidence to justify its use in the treatment of MASH 41