By addressing underlying issues such as inflammation and insulin resistance, these medications can transform lives
Eight major RCTs of GLP-1RAs have investigated the cardiovascular outcomes, including the ELIXA trial of lixisenatide (250), the EXSCEL trial of exenatide ER (251), the LEARDER trial of liraglutide (252), the SUSTAIN-6 trial of subcutaneous semaglutide (253), the HARMONY trial of albiglutide (228), the REWIND trial of dulaglutide (254), the PIONEER trial of oral semaglutide (255), and the SELECT trial of subcutaneous semaglutide (199)
In line with NICE guidance, lower BMI thresholds may be appropriate for people from some ethnic groups
You start a GLP-1 medication expecting appetite suppression, weight loss, maybe some nausea
14.3 Obesity Between 1960 and 1980, obesity prevalence among adults aged 20-49 was between 13% and 15% (204)
GLP-1 medications, bariatric surgery, peptide therapy, and other medical weight loss treatments require evaluation by a licensed healthcare provider