Although glutathione reductase has been an attractive target for drug development, no successful glutathione reductase-related therapeutics have been implemented in pulmonary disease to date
in fibroblast culture models it stimulates collagen, elastin, and glycosaminoglycan synthesis at picomolar to nanomolar concentrations (10 to 10 M), and modulates metalloproteinase (MMP-1, MMP-2, MMP-9) activity and their inhibitors (TIMP-1, TIMP-2), functioning as a general regulator of extracellular matrix remodeling ( Mechanistic research establishes that GHK activates TGF- and integrin 1 pathways during tissue repair, attracts immune and endothelial cells to wound sites, and restores gene expression patterns toward a healthier fibroblast phenotype in models of aging and radiation damage ( A 2018 review in IJMS characterizes its role in collagen production, nerve outgrowth stimulation, and dermal stem cell marker expression ( For Research Use Only
doi: 10.1016/S0893-133X(98)00067-0
Often referred to as the Master Antioxidant, it is found in every cell of the human body
Professional clinic-ready packaging
Progressive depletion of cellular glutathione is also used as a mechanism by many viruses to control their replication cycle during infection
