The objective of the STEP 1 study was to compare the effect of a semaglutide SC 2.4 mg injection once weekly versus placebo as an adjunct to a reduced-calorie diet and increased physical activity in patients with overweight or obesity on body weight (primary objective), and cardiovascular risk factors, clinical outcome assessment, glucose metabolism, and other factors related to body weight (secondary objectives)
Long F, Challa TD, Ding L, et al
Subjects were advised to refrain from eating too much spicy food at breakfast time during the study period
Side effects: Gastrointestinal issues such as nausea, vomiting, and diarrhea are common and often lead to discontinuation
Another recent study found that most cavaliers do not develop SM until after their third birthday and as late as age 6 years
Effectiveness of intermittent fasting for weight loss: Its not just when you eat, but what you eat, too