Methods Participants The participants of the present study are a subcohort ( n = 60) from the TearAD study (clinicaltrails.gov: NCT05655793) 22 , a multicenter study that includes 200 participants from two memory clinics in the Netherlands, namely Maastricht University Medical Center + and the Amsterdam University Medical Center
Safety FDA found no clinical studies establishing safety, no pharmacokinetic data and no human immunogenicity or aggregation studies
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Proteoglycan synthesis accelerates to provide structural integrity to the extracellular matrix