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Both RAW 264.7 cells and peritoneal macrophages were maintained in RPMI 1640 medium supplemented with 10% fetal bovine serum, 5% CO, and 95% air at 37C

The findings suggest that SSRIs alter the activities of placental enzymes, which could lead to disturbances in maternal steroid hormone homeostasis and biometabolism, thereby posing a risk to both the developing fetus and the pregnant woman