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10.1016/j.yebeh.2011.07.002 Epilepsy Behav

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PT-141 takes a fundamentally different approach

The C-terminal segment takes part in interactions with the N-terminal -helix of the extracellular domain, the extracellular tip of the transmembrane helix 1 of the GLP-1 receptor, and the extracellular loop 1 of the GIP receptor